Feasibility of Using Depth of Sedation Monitors to Reduce Delirium in Critically Ill Patients
DOSM
1
PURPOSE
The purpose of the DOSM study is to evaluate whether depth of sedation monitors can be effectively implemented in ICU settings. By providing more accurate and individualized sedation data, the study aims to reduce the risk of delirium in critically ill patients and improve their short- and long-term outcomes.
2
PROGRESS
100
100
patients enrolled
(as of Oct. 2025)
3
FUTURE
The findings from this feasibility study will lay the foundation for a larger randomized controlled trial that compares sedation guided by these monitors to standard care. If successful, this future trial could lead to a shift in ICU sedation practices, promoting personalized care that enhances patient recovery, reduces complications like delirium, and potentially lowers healthcare costs.
What is DOSM?
The DOSM study is a pilot observational trial evaluating the feasibility of using depth of sedation monitors in ICU patients who require mechanical ventilation. It investigates how these monitors correlate with clinical outcomes like delirium, sedation levels, and recovery.
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Why is this important?
Delirium is common and harmful in ICU patients, especially those receiving sedation, and current assessment methods are often unreliable. This study addresses a critical gap by testing a more objective and personalized approach to sedation management.
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What is involved in the study?
The research team designs and oversees the study, including patient enrollment, monitoring using Masimo SedLine®, data collection, and analysis. Our goal is to assess feasibility and gather insights to guide future clinical trials.
