CYCLE Pilot: A Pilot Randomized Study of Early Cycle Ergometry versus Routine Physiotherapy in Mechanically Ventilated Patients
(Victoria Hospital)
CYCLE
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PURPOSE
The purpose of the CYCLE Polit Study is to identify if early in-bed cycling plus routine physiotherapy in mechanically ventilated patient can improve the primary outcomes of physical function at 3 days after ICU discharge, and secondary outcomes, such as strength, frailty, psychological distress, quality of life, mortality, and healthcare utilization. The study also aims to determine the cost-effectiveness of this intervention compares to with only routine physiotherapy.
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PROGRESS
100%
patients enrolled
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FUTURE
CYCLE is aimed to use high quality of data to advance healthcare knowledge by informing the early rehabilitation management of previously ambulatory, critically ill, mechanically ventilated patient, as well as providing justification for equipment purchase and additional personnel time needed to implement cycling in the ICU setting based on the economic evaluation.
What is CYCLE?
The CYCLE study compares early in-bed cycling and routine physiotherapy to routine physiotherapy alone in critically ill, mechanically ventilated patients. This is a multi-centred, open label randomized control trial focused on adults receiving mechanically ventilation in a medical-surgical ICU setting.
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Why is this important?
Mechanically ventilated patients often receive prolonged bedrest and are less involved in physiotherapy at the beginning of ICU admission. In-bed cycling is a novel technology that may help such patients to prevent muscle weakness by receiving early exercises, and previous studies have shown that the interventions are safe.​
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What is involved in the study?
Adult patients admitted to the ICU that are mechanically ventilated and could ambulate independently at baseline would be considered to enroll in the study. Participants will be randomized into one of the study arms, and the intervention will occur for a maximum of 28 days, with a 90-days follow up for both arms.
Study Arms
Intervention Arm: Cycling
Patient will be receiving 30 minutes/day of in-bed cycling in addition to routine physiotherapy interventions, 5 days per week, during their ICU stay. Cycling will occur for a maximum of 28 days, or patient is capable to march on the spot for 2 consecutive days.
Control Arm: Routine Care
Patient will be receiving routine physiotherapy interventions per current institutional practice.
